And seeing that this thread is about treating cancers I offer a long winded but thorough report from my friend regarding his apparently successful treatment -
Extracted from his newsletter -
During this time my son spent many hours researching additional ways to help treat the cancer. Aside from the immediate hormone treatment I was given in hospital and early in December he contacted Dr William Makis, a Canadian Radiologist who provides individual protocols to help fight patients with cancer through various repurposed medicines like Ivermectin and Menbendazole accompanied with supplements like Melatonin. Dr Makis kindly accepted me as a patient and I was immediately put on high dosages of all three of these amongst other things.
In the last few days Dr Makis, put up this report on my progress on ‘X’. This can be read on the links below. A fuller explanation though is added below in this report
https://threadreaderapp.com/thread/1895800117204025810.html
https://x.com/MakisMD/status/1895800117204025810?t=TlJVNVcdDwO5ndJfWqdUWw&s=03
Ivermectin started at 1mg per kg body weight and 500mg per kg body weight for Menbendazole. Melatonin was started at 100mg a day. After the first month these amounts were increased. Also during these early days, my son had contacted RGCC International. This was at the suggestion of an American consultant whose time was also kindly paid for by a generous donor.
RGCC is an organisation that provides an advanced cancer diagnostics test that suggests both conventional and alternative treatments based on the blood work and interaction with these compounds with the cancer cells within their labs. Their report opened up a variety of medications and supplements that we would have not known to have a positive effect. Some of them were not cheap but with the fund going well, we were able to take that route. One of which is a potent form of Astaxanthin called Valasta which has incredible testimonials for many different illnesses and ailments.
You may be familiar with the German doctor and Nobel prize winner Otto Warburg. In the 1920’s he observed the Warburg effect, where most cancers prefer to use aerobic Glycolysis, the process of using glucose in the presence of oxygen, even when there's enough oxygen to fully metabolize it and lactic acid fermentation. It is a process that breaks down sugars to produce energy and lactic acid for energy generation rather than the mechanisms used by non-cancerous cells.
We have learned that some cancers, such as prostate cancer, can switch metabolic pathways to enhance survival. When glucose is low, these cancer cells can shift to the oxidative phosphorylation (OXPHOS) pathway, using lipids (fatty acids), glutamine, lactate, or acetate as fuel, a process that occurs inside the mitochondria.
Professor Thomas Seyfried, a specialist in biology, genetics, and biochemistry at Boston College, argues that cancer is primarily a metabolic disease rather than a genetic disorder, with the root cause lying in dysfunctional cellular energy metabolism. Since cancer thrives on glucose and glutamine, he recommends eliminating these from the diet through fasting and a ketogenic diet. However, while these methods may deprive cancer cells of their primary fuel sources, they can also starve all cells of ATP.
Initially, I believed that increasing oxygen levels through therapies like hyperbaric oxygen and red light therapy would help in my fight against cancer. However, I’ve come to realize that this approach is more complex. Oxygen can enhance OXPHOS, and tumours that rely on this pathway or angiogenesis may grow faster in oxygen-rich environments. A 2020 study found that exposure to high concentrations of oxygen increased reactive oxygen species (ROS) production, which could fuel cancer cell growth. The relationship between mitochondria and oxidative phosphorylation is critical for healthy cellular energy production, and it’s clear that having the right amount of oxygen—neither too much nor too little—is essential for optimal cellular function. Given these risks, I’ve opted against these therapies to avoid potentially exacerbating cancer growth.
That's not to say oxygen rich conditions can't help in the fight against cancer but it wasn't as risk I was willing to take and for those reasons we decided to stop the hyperbaric oxygen chamber and red light therapy in case we were doing more harm than good and for us to know whether the cancer is relying on the OXPHOS pathway before using these machines would require regular testing to ensure safety and that realistically wasn't an option for me and we didn't want to rely on the hope that it wasn't.
Something else we learned was that cancer cells have pump mechanisms that help reduce the effectiveness of treatments.
Cancer cells have efflux pumps. A protective mechanism that excretes compounds designed to destroy the cell and several supplements and repurposed medicines can inhibit these pump mechanisms to increase the duration of the compound within the cell. This enhances its efficacy to weaken and destroy the cancer.
Unfortunately, efflux pump inhibitors are currently not available under the NHS but hopefully will be in the near future.
Some of the supplements and medications listed below, recommended by Dr. Makis and RGCC, have been shown to inhibit these pumps.
The use of other repurposed drugs has been found to be highly effective in reducing the risk of cancer recurrence.
One of the main reasons for cancer recurrence after remission is that many treatments are unable to target and eliminate cancer stem cells. cancer stem cells (CSCs) are a small subpopulation of cells within a tumour that possess the ability to self-renew, differentiate, and drive tumour growth.
That these supplements and repurposed drugs are not being widely used is likely by design for financial reasons. But emerging research suggests that the combination of Ivermectin and Mebendazole has been shown to damage or destroy cancer stem cells in some patients which greatly decreases the chances of cancer returning
The blood results from RGCC identified many other potential medications/ supplements which they had found to be measurably successful with my cancer.
Below is my current supplement protocol that you may find of interest/ use.
pubmed.ncbi.nlm.nih.gov
